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[10] [11] [12] [13] [14] Rich Van Konynenburg first postulated a depletion of glutathione was at the heart of many of the symptoms of CFS/ME, but quickly added information about methylation when he realized that the two were connected

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Fact 4: NAC Has Diverse Clinical Applications Respiratory health: bronchitis and COPD NAC has been used clinically for various respiratory conditions due to its mucus-thinning properties

13 Future directions Future advances in GSH-responsive nanomedicine should focus on clinically relevant development rather than proof of concept designs

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